Fig 1: Overexpression of PDLIM2 attenuated the inflammatory response in HFLSs-RA. A. ELISA assay was used to detect the expression of TNF-α, IL-1β and IL-6. B. The expression of Cox2 and iNOS were detected with Western blot. ***p < 0.001 vs Ov-NC.
Fig 2: Overexpression of PDLIM2 inhibited the migration of HFLSs-RA. A. Wound healing was used to detect the migration of HFLSs-RA. B.T he expression of MMP-2 and MMP-9 in HFLSs-RA after transfection were detected by western blot. ***p < 0.001 vs Ov-NC.
Fig 3: Interfering KLF10 reversed the inhibitory effects of PDLIM2 overexpression on the inflammation of HFLSs-RA through NF-κB pathway. A. ELISA assay was used to detect the expression of TNF-α, IL-1β and IL-6 in HFLSs-RA after transfection. B. The expression of Cox2 and iNOS in HFLSs-RA after transfection were detected with Western blot. C. The expression of NF-κB pathway-related proteins in HFLSs-RA after transfection were detected with Western blot. ***p < 0.001 vs Ov-NC.#p < 0.05, ##p < 0.01, ### p < 0.001 vs Ov-PDLIM2 + shRNA-NC.
Supplier Page from Abcam for Anti-PDLIM2 antibody